The following is a listing of the Plasma donor centres:
| ne | Name | Address |
| Eastern Cape | Berea DC | Deveraux Avenue, East London |
| Eastern Cape | Becon Bay DC | Beacon Bay Crossing |
| Eastern Cape | Walker DC | Walker Drive, Sherwood |
| Eastern Cape | PE HQ DC | Buckingham Road, Mount Croix |
| Egoli | Bedfordview DC | 25 Ernest Oppenheimer Street, Bruma |
| Egoli | Lenasia DC | 82 Gemsbok Street, Signet Terrace |
| Egoli | Maponya Mall DC | 2127 Chris Hani Road, Soweto |
| Egoli | Beacon Road DC | 31 Beacon Road, Building 5, Florida North |
| Egoli | Germiston DC | Cnr Webber & Beacon Road, Lambton |
| Egoli | Southdale DC | Southdale Shopping Centre, Southdale |
| Egoli | Krugersdorp DC | Cnr Voortrekker & Van Oordt Road, Monument |
| Egoli | The Colony DC | Jan Smuts Avenue, Craighall |
| Egoli | Alberton DC | Cnr Voortrekker & Du Plessis Road, Florientia |
| Egoli | Fourways DC | Cnr Forest Road & Sunset Avenue, Fourways |
| Egoli | Westgate DC | Ondekkers Road, Roodepoort |
| Egoli | Northgate DC | Cnr Olievenhout and Northumberland Avenue, Northriding |
| FSNC | Bethlehem DC | River Walk Centre, Shop 1A, Muller Street, Bethlehem |
| FSNC | Bloem Plaza DC | Shop 44 & 45, Bloemfontein |
| FSNC | Hypermarket Fixed site | 111 Benade Drive, Fichardtpark, Bloemfontein |
| FSNC | Kimberley DC | 169 Du Toitspan Road, Kimberley |
| KZN | Hillcrest DC | 50 Old Main Road, Hillcrest |
| KZN | North Durban DC | 53 Adelaide Tambo, Opposite Library, Durban North |
| KZN | Loop St DC | Jabu Ndlovu Street, Pietermaritzburg |
| KZN | Westwood Mall DC | Shop L030 Westwood Mall 16 Lincoln Terrace Westville |
| Mpumalanga | Middleburg DC | 10 Church Street, Middelburg |
| Mpumalanga | Safeways DC | Nelson Mandela Drive, Emalahleni |
| Mpumalanga | Riverside DC | Riverside Mall, Entrance 5, Shop 219C , Nelspruit |
| Mpumalanga | Lydenburg DC | Pick ‘n Pay Centre, 53 Kantoor Street, Lydenburg |
| Mpumalanga | Secunda DC | Unit 4A, Heunis Street, Secunda |
| Mpumalanga | Bethal DC | 41Du Plooy Street, Bethal |
| Mpumalanga | Ilanga Mall DC | SR02 West Acres X38, Nelspruit |
| Northern | Centurion DC | Jean Village Centre, Jean Avenue, Centurion |
| Northern | Hatfield DC | Hatfield Plaza, 1122 Burnett Street, Hatfield |
| Northern | Polokwane DC | 153 Potgieter Avenue, Polokwnae |
| Northern | Rustenburg DC | Lifestyle Square, Beyers Naude Drive, Rustenburg |
| Northern | Wonderpark DC | Shop 113, Heinrich Avenue, Karenpark |
| Northern | Kolonnade DC | Sefako Makgato Drive, Montana |
| Northern | Atterbury DC | Atterbury Drive, Faerie Glen |
| Vaal | River Square DC | Cnr Nile Dr & General Hertzog Street, Three Rivers |
| Vaal | Springs DC | Wit Road, Spring |
| Vaal | Kempton Park DC | 20 Central Avenue, Kempton Park |
| Vaal | East Rand Square DC | East Rand Mall, Entrance 2, Shop 155/156, Boksburg |
| Vaal | Benoni DC | 42 14th Avenue, Northmead, Benoni |
| Vaal | Potchefstroom DC | Esselen Street, Potchefstroom |
| Vaal | Carnival Mall DC | Heidelberg Road & Airport Road, Dalpark, Brakpan |
The following is a listing of the Platelets donor centres:
| Province | Site Name / Department | Site Physical Address |
| Eastern Cape | Port Elizabeth HQ | Provincial Hospital Grounds, Buckingham Road, Port Elizabeth |
| Eastern Cape | Walker Drive | Shop U 40, Cnr Kabega &Walker Drive Shopping Centre, Walker Drive, Sherwood, Port Elizabeth |
| Gauteng | Alberton | Alberton Shopping Centre Shop no 6 C/o of Du Plessis and Voortrekker Road Alberton |
| Gauteng | Bedfordview | Park Meadows shopping Centre, Bedfordview (New Address 31.08.2022) Old Adress: Finance House 25 Ernest Oppenheimer Str Bruma, Bedfordview |
| Gauteng | Egoli South Branch HQ / Beacon Road | No 31, Beacon Road Building No 5 Bergshoff Office Park Florida North |
| Gauteng | Fourways | Shop No 12, Forest Design and Décor Centre Corner Forest Road and Sunset Avenue Pineslopes |
| Gauteng | Maponya | Shop 410 1st Floor Maponya Mall, Pimville, 1808 Soweto Chris Hani Baragwanath Road Soweto |
| Gauteng | Monument | Anthos Shopping Centre, Shop 7&8 Voortrekker Road Monument, Krugersdorp |
| Gauteng | Northgate | Shop No 609 Phase 6 Northgate Shopping Centre Corner Olievenhout and Northumberland Avenues Northriding |
| Gauteng | Southdale | Shop 19 Southdale Shopping Centre Alamein Street Southdale |
| Gauteng | Westgate | Mon-Fri 09H00 – 17H00. Sat 08H00 – 14H00. Sun 08H00 – 14H00 |
| Northern Cape | Kimberley | 169 Du Toitspan Road, Belgravia Kimberley |
| Free State | Victorian Square | Victorian Square, Shop 34 & 35, Cnr Second Avenue and President & Reitz Street, Westdene Bloemfontein |
| KZN | Hillcrest | Shop No 20, The Colony, 50 Old Main Rd Hillcrest |
| KZN | Loop Street | 294 Loop Street (cnr Loop St and Henrietta St) Pietermaritzburg |
| KZN | Westwood Mall DC | L030A&B Westwood Mall , 16 Lincoln Terrace ,Westville |
| Mpumalanga | Middelburg | Shop 13, Wonderpark Spar Centre, 29 Church Street, Middelburg |
| Mpumalanga | Middelburg | Shop 13, Wonderpark Spar Centre, 29 Church Street, Middelburg |
| Gauteng | Kolonnade | Kolonnade Shopping Centre, Shop U31, 1st floor, Sefako Makgatho Drive & Enkeldoorn Ave, Montana Park, Pretoria, 0159 |
| Gauteng | Centurion | Shop 15B, Jean Village Shopping Complex, C/O Jean Ave & Gerhard Street, Centrurion |
| Gauteng | Hatfield | Shop F1G 27 Hatfield Plaza 1122 Burnette St Hatfield 0083 |
| Gauteng | Benoni | 42 14th Avenue, Northmead, Benoni |
| Gauteng | Kempton Park | Law Chambers Building, 20 Central Avenue, Kempton Park |
| North West | Klerksdorp | Shop 63, Flamwood Walk Shopping Centre, Brother Patrick Lane, Klerksdorp |
| Gauteng | River Square (Three Rivers) | Shop No C2, River Square Shopping Centre, Nile Drive, Three Rivers |